Disease: Cardiac fibrosis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VPS51 Q9UID3 VPS51 subunit of GARP complex 1.1E-08 0.452 0.846
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
TRPM7 Q96QT4 transient receptor potential cation channel subfamily M member 7 Ion channel 5.2E-16 0.531 0.731
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
RNF111 Q6ZNA4 ring finger protein 111 1.00 0.700 0.500
PXDN Q92626 peroxidasin Enzyme 2.5E-07 0.647 0.500
PLN P26678 phospholamban 0.45 0.595 0.577
OGG1 O15527 8-oxoguanine DNA glycosylase 3.9E-12 0.453 0.808
NOX4 Q9NPH5 NADPH oxidase 4 Enzyme 5.8E-20 0.471 0.885
MIR21 microRNA 21 0.363 0.846
MIR126 microRNA 126 0.447 0.846
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
GRK5 P34947 G protein-coupled receptor kinase 5 Kinase 0.68 0.588 0.769
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
FOXM1 Q08050 forkhead box M1 7.4E-04 0.441 0.769
DMD P11532 dystrophin 1.00 0.423 0.923